Nutrition
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We investigated whether food restriction offers protection against the toxicity of carbon tetrachloride (CCl(4)) and, if so, at what percentage of restriction. ⋯ The present results suggested that food restriction can minimize drug-related increases in peroxidation and protect the system against drug toxicity, presumably by induction of antioxidant potential.
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Randomized Controlled Trial Clinical Trial
Effect of supplementing a high-fat, low-carbohydrate enteral formula in COPD patients.
One of the goals in treating patients with chronic obstructive pulmonary disease (COPD) who suffer from hypoxemia, hypercapnia, and malnutrition is to correct the malnutrition without increasing the respiratory quotient and minimize the production of carbon dioxide. This 3-wk study evaluated the efficacy of feeding a high-fat, low-carbohydrate (CHO) nutritional supplement as opposed to a high-carbohydrate diet in COPD patients on parameters of pulmonary function.S METHODS: Sixty COPD patients with low body weight (<90% ideal body weight) were randomized to the control group, which received dietary counseling for a high-CHO diet (15% protein, 20% to 30% fat, and 60% to 70% CHO), or the experimental group, which received two to three cans (237 mL/can) of a high-fat, low-CHO oral supplement (16.7% protein, 55.1% fat, and 28.2% CHO) in the evening as part of the diet. Measurements of lung function (forced expiratory volume in 1 s or volume of air exhaled in 1 s of maximal expiration, minute ventilation, oxygen consumption per unit time, carbon dioxide production in unit time, and respiratory quotient) and blood gases (pH, arterial carbon dioxide tension, and arterial oxygen tension) were taken at baseline and after 3 wk. ⋯ This study demonstrates that pulmonary function in COPD patients can be significantly improved with a high-fat, low-CHO oral supplement as compared with the traditional high-CHO diet.
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Comparative Study
Early versus late nutrition support in premature neonates with respiratory distress syndrome.
This retrospective study evaluated two different modes of nutrition supplementation in premature neonates with respiratory distress syndrome. ⋯ Early nutrition to maintain a positive energy balance in premature neonates with respiratory distress syndrome is beneficial.
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Comparative Study
Comparison of formulaic equations to determine energy expenditure in the critically ill patient.
Inappropriate energy intake can negatively affect patient outcome during critical illness. Measuring energy expenditure via indirect calorimetry (IC) is the most accurate method of determining needs. Often predictive equations are used because IC is not available at all institutions or for all populations. ⋯ Predictive equations such as the Harris-Benedict equation multiplied by a stress factor of 1.6 and the Swinamer equation may be accurate enough for short-term nutrition support of critically ill patients when IC is unavailable.
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Randomized Controlled Trial Clinical Trial
Weight loss associated with a daily intake of three apples or three pears among overweight women.
We investigated the effect of fruit intake on body weight change. ⋯ Intake of fruits may contribute to weight loss.