Journal of clinical anesthesia
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Review Meta Analysis
Dexamethasone for the prevention of postoperative sore throat: a systematic review and meta-analysis.
Intraoperative dexamethasone reduces the incidence of postoperative sore throat for up to 24 hours and postoperative hoarseness for 1 hour.
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General anesthesia may lead in patients to unexpected and adverse reactions including toxicity. Glutathione S-transferases (GSTs) are enzymes responsible for the detoxification process of anesthetic agents. ⋯ The biochemical function and specific properties of GST render it a prognostic biomarker. This review demonstrates that GST can be valuable and promising toxicity indicator in patients undergoing general anesthesia.
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Randomized Controlled Trial Comparative Study
A prospective study comparing the onset and analgesic efficacy of different concentrations of levobupivacaine with/without dexmedetomidine in young children undergoing caudal blockade.
To investigate the onset and analgesic effect of adding dexmedetomidine to levobupivacaine for caudal block in young children. ⋯ Dexmedetomidine added to levobupivacaine does not have a significant effect on the onset time; however, it prolongs the duration of analgesia during caudal block in children.
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Randomized Controlled Trial Comparative Study
Comparison of sugammadex and conventional reversal on postoperative nausea and vomiting: a randomized, blinded trial.
To determine whether the new selective binding agent sugammadex causes less postoperative nausea and vomiting (PONV) than the cholinesterase inhibitor neostigmine. ⋯ Nondepolarizing neuromuscular blocking antagonism with sugammadex speeds recovery of neuromuscular strength but only slightly and transiently reduces PONV compared with neostigmine and atropine.
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Observational Study
The impact of breastfeeding on postpartum pain after vaginal and cesarean delivery.
Oxytocin may play a role in pain modulation. The analgesic effects of breastfeeding with its associated endogenous oxytocin release have not been well investigated. To determine the impact of breastfeeding on incisional, perineal, and cramping pain after cesarean and vaginal delivery. ⋯ There was no analgesic effect on incisional pain during breastfeeding, indicating that endogenous oxytocin associated with breastfeeding may not play a significant role in postpartum cesarean wound pain modulation. Breastfeeding increased cramping pain after vaginal and cesarean delivery. The increase in cramping pain is most likely due to the breastfeeding-associated oxytocin surge increasing uterine tone.