BMJ : British medical journal
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Randomized Controlled Trial Multicenter Study
Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial.
To determine whether tocilizumab improves clinical outcomes for patients with severe or critical coronavirus disease 2019 (covid-19). ⋯ In patients with severe or critical covid-19, tocilizumab plus standard care was not superior to standard care alone in improving clinical outcomes at 15 days, and it might increase mortality.
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Meta Analysis
Efficacy and safety of antidepressants for the treatment of back pain and osteoarthritis: systematic review and meta-analysis.
To investigate the efficacy and safety of antidepressants for back and osteoarthritis pain compared with placebo. ⋯ PROSPERO CRD42020158521.