BMJ : British medical journal
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BMJ
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Meta Analysis
Systematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamol.
To evaluate the comparative efficacy and tolerability of paracetamol-dextropropoxyphene combination and paracetamol through a systematic overview of randomised controlled trials. ⋯ On the basis of data on analgesic efficacy and acute safety in both head to head and indirect comparisons, there is little objective evidence to support prescribing a combination of paracetamol and dextropropoxyphene in preference to paracetamol alone in moderate pain such as that after surgery.