Urology
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To develop and test an artificial neural network (ANN) for predicting biochemical recurrence based on the combined use of pelvic coil magnetic resonance imaging (pMRI), prostate-specific antigen (PSA) measurement, and biopsy Gleason score, after radical prostatectomy and to investigate whether it is more accurate than logistic regression analysis (LRA) in men with clinically localized prostate cancer. ⋯ Using the pMRI findings, the ANN was superior to LRA, predictive tables, and nomograms to predict biochemical recurrence accurately. Confirmatory studies are warranted.
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Comparative Study
Efficiency and cost of treating proximal ureteral stones: shock wave lithotripsy versus ureteroscopy plus holmium:yttrium-aluminum-garnet laser.
To compare the success rates, cost effectiveness, and efficiency of ureteroscopy (URS) and extracorporeal shock wave lithotripsy (ESWL) for proximal ureteral stones. ⋯ The results of this study indicate that URS is more efficient and cost-effective for stones up to and larger than 1 cm with similar complication rates compared with ESWL.
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Randomized Controlled Trial Clinical Trial
Tranexamic acid in control of primary hemorrhage during transurethral prostatectomy.
To determine whether short-term treatment of patients about to undergo transurethral resection of the prostate (TURP) with tranexamic acid (TXA) would be beneficial in reducing the associated blood loss. ⋯ Short-term TXA treatment is effective in reducing the operative blood loss associated with TURP.
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To evaluate the effectiveness of transvaginal manual therapy of the pelvic floor musculature (Thiele massage) in symptomatic female patients with interstitial cystitis and high-tone dysfunction of the pelvic floor. ⋯ Thiele massage appears to be very helpful in improving irritative bladder symptoms in patients with interstitial cystitis and high-tone pelvic floor dysfunction in addition to decreasing pelvic floor muscle tone.
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To assess the importance of sex and the prevalence of sexual dysfunction among middle-aged and older adults throughout the world. Increasing life expectancy has been accompanied by improvements in the health of the middle-aged and elderly, but little is known about how this has affected their sexual experience. ⋯ The results of our study indicate that sexual desire and activity are widespread among middle-aged and elderly men and women worldwide and persist into old age. The prevalence of sexual dysfunctions was quite high and tended to increase with age, especially in men. Although major between-country differences were noted, this global study revealed some clear and consistent patterns.