Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Feb 1995
Randomized Controlled Trial Clinical TrialPotency and maintenance requirement of atracurium and vecuronium given alone or together.
A synergism exists between some competitive muscle relaxants. However, maintenance requirement of a combination of muscle relaxants has been evaluated only in paediatric patients. We studied 45 elective adult surgical patients (ASA I-II) during propofol-alfentanyl-N2O-O2-anaesthesia. ⋯ Thus, a significant potentiation was maintained also during the course of anaesthesia. A cAV had an effect like one intermediate-acting agent. If a cAV is used instead of using atracurium or vecuronium alone, the maximal reduction of drug consumption would be approximately 30%.
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Acta Anaesthesiol Scand · Feb 1995
Randomized Controlled Trial Comparative Study Clinical TrialPrilocaine reduces injection pain caused by propofol.
Propofol, which is commonly used for outpatient anaesthesia, may evoke pain during infusion. Forty-eight patients (ASA-I-II) undergoing elective uterine dilatation and curettage received randomly in a standardised fashion: A: Propofol mixed with prilocaine; B: Propofol and lidocaine; C: Propofol with prilocaine+lidocaine (equal amounts) or D: Propofol and saline. The final ratio of propofol:local anaesthetic/saline was 9:1 in all mixtures. ⋯ Another twenty-two comparable patients were given 30 mg of ketorolac or an equal volume of saline intramuscularly 45-60 minutes prior to propofol. Ketorolac given before propofol did not reduce pain on injection. This indicates that inhibition of the cyclooxygenase pathway of arachidonic acid metabolism does not play a major role in the reduction of this pain.
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Acta Anaesthesiol Scand · Feb 1995
Case ReportsIntraoperative anaphylaxis caused by a hydatid cyst.
The incidence of the hydatid disease is still high in some regions of the Mediterranean. A serious, but rare, peroperative complication is IgE-mediated anaphylaxis, as a result of passing of the highly antigenic hydatid cyst content into the bloodstream. We present here a case of anaphylactic reaction in a patient who underwent surgical treatment of hydatid cyst.
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Acta Anaesthesiol Scand · Feb 1995
Comparative StudyHow are haemodynamic and metabolic responses to haemorrhage influenced by segmental thoracic and thoracolumbar epidural analgesia? An experimental study in dogs.
To determine the effects of the spread of sympathetic blockade administered prior to haemorrhage on haemodynamic and metabolic responses to haemorrhage, we compared these responses among dogs treated by segmental thoracic epidural analgesia, thoracolumbar epidural analgesia and general anaesthesia. Group 1 of six dogs received 0.2% halothane plus epidural analgesia ranging from C4 to T5, group 2 of seven 0.2% halothane plus epidural analgesia ranging from C5 to L7, and group 3 of eight 0.9% (1 MAC) halothane anaesthesia. A volume of 35 ml.kg-1 was bled over 30 min. ⋯ The plasma epinephrine concentration increased immediately after haemorrhage and then decreased slowly in groups 1 and 3. In group 2 it remained unchanged at the lower level. The decreases in mean arterial pressure, systemic vascular resistance and base excess were significantly larger in group 2 than in groups 1 and 3.(ABSTRACT TRUNCATED AT 250 WORDS)
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Acta Anaesthesiol Scand · Feb 1995
Comparative StudyDeath associated with anaesthesia and surgery in Finland in 1986 compared to 1975.
Mortality associated with anaesthesia and surgery in Finland in 1986 was studied using a retrospective method and was compared with the results of a similar study performed in 1975. The total number of procedures was 325,585. 570 patients fulfilled one of the three criteria: 1. The patient died within three days of a procedure needing anaesthesia. 2. ⋯ At the same time there was also a significant increase in recovery room and intensive care facilities. Surgery was the main contributing factor in the death of 22 (frequency 0.68/10,000 procedures), and anaesthesia in the death of five (frequency 0.15/10,000 procedures) patients. The role of surgery had decreased to about one third and the role of anaesthesia to less than one tenth as the main cause of death associated with anaesthesia and surgery compared to the year 1975. 95.3% of all the patients died mainly because of co-existing medical or surgical disease.