Acta psychiatrica Scandinavica
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Acta Psychiatr Scand · Sep 2010
ReviewAn update on the role of glutamate in the pathophysiology of depression.
To review the literature on the involvement of glutamate (Glu), including its interactions with other neurochemical systems, in the pathophysiology of depression. ⋯ A growing body of evidence indicates that the glutamatergic system is involved in the pathophysiology of depression, and may represent a target for intervention.