Acta psychiatrica Scandinavica
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Acta Psychiatr Scand · Oct 2011
ReviewEndocannabinoid system dysfunction in mood and related disorders.
The endocannabinoid (EC) system is widely distributed throughout the brain and modulates many functions. It is involved in mood and related disorders, and its activity may be modified by exogenous cannabinoids. This article examines the therapeutic potential of cannabinoids in psychiatric disorders. ⋯ Research is needed to elucidate the role of the EC system in psychiatric disorders and for clinical trials with THC, CBD and synthetic cannabinoids to assess their therapeutic potential.