European journal of ophthalmology
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Randomized Controlled Trial Multicenter Study Comparative Study
Intravitreal pegaptanib combined with diode laser therapy for stage 3+ retinopathy of prematurity in zone I and posterior zone II.
To investigate efficacy of intravitreal injection of pegaptanib and laser photocoagulation for treatment of stage 3+ retinopathy of prematurity (ROP) affecting zone I and posterior zone II, and to compare the results in terms of regression, development of peripheral retinal vessels, and final structural outcome with conventional laser photocoagulation or combined with cryotherapy. ⋯ Results of this study support the administration of intravitreal pegaptanib as useful therapy in the management of stage 3+ ROP.