International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
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Int. J. Gynecol. Cancer · Mar 2013
ReviewDiabetes mellitus and ovarian cancer risk: a systematic review and meta-analysis of observational studies.
The objective of this study was to evaluate the epidemiologic association between diabetes and risk of ovarian cancer. ⋯ This study suggests that women with diabetes have a moderately increased risk of ovarian cancer.
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Int. J. Gynecol. Cancer · Mar 2013
Radical surgery with individualized postoperative radiation for stage IB cervical cancer: oncologic outcomes and severe complications.
The objective of this study was to compare morbidity and outcome following radical surgery with or without adjuvant radiation therapy (RT) in the treatment of stages IB1-IB2 cervical carcinoma. ⋯ The majority of women with stages IB1-IB2 cervical cancer undergoing radical surgery do not require adjuvant RT, have excellent oncologic outcome, and have low severe complication rates. Nearly one third of our patients required postoperative radiation, with no statistically significant increase in severe complication rate and with similar oncologic outcomes compared with the surgery-only cohort. These data support the continued practice of radical surgery with individualized postoperative radiation for these patients.
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Int. J. Gynecol. Cancer · Mar 2013
End-of-life care of women with gynecologic malignancies: a pilot study.
There are limited data regarding the end-of-life care for women with gynecologic malignancies. We set out to generate pilot data describing the care that women with gynecologic malignancies received in the last 6 months of life. Patient demographics, patterns of care, and utilization of palliative medicine consultation services were evaluated. ⋯ End-of-life care for patients with gynecologic malignancies often includes futile, aggressive treatments and invasive procedures. It is unknown whether these measures contribute to longevity or quality of life. These pilot data suggest that factors for implementation of timely hospice referral, family support, and legacy building should include specialists trained in palliative medicine.