Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
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J Stroke Cerebrovasc Dis · Mar 2007
Morphologic assessment of middle cerebral artery aneurysms for endovascular treatment.
Aneurysms of the middle cerebral artery (MCA) trifurcation region are underrepresented in large series of endovascularly treated aneurysms. The purpose of our study was to evaluate the incidence of specific morphologic features of MCA bifurcation aneurysms that may affect suitability for endovascular treatment. ⋯ The majority of MCA aneurysms have morphologic features such as a dome to neck ratio less than 2:1 or branch vessel incorporation that may make them unsuitable for endovascular treatment using conventional intra-aneurysmal coiling.
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J Stroke Cerebrovasc Dis · May 2005
Intravascular Cooling in the Treatment of Stroke (ICTuS): early clinical experience.
We sought to evaluate the safety and feasibility of mild therapeutic hypothermia using an endovascular temperature management system in awake acute ischemic stroke patients. The Intravascular Cooling in the Treatment of Stroke (ICTuS) study was an uncontrolled, multicenter development and feasibility study of conscious patients (n = 18) presenting within 12 hours of onset of an acute ischemic stroke at 5 clinical sites in the United States. Enrolled patients were to undergo core temperature management using an endovascular cooling system to induce and maintain mild, therapeutic hypothermia (target temperature of 33.0 degrees C) for a period of either 12 or 24 hours, followed by controlled rewarming to 36.5 degrees C over the subsequent 12-hour period. ⋯ Increasing the duration of hypothermia administration from 12 hours to 24 hours did not appear to increase the incidence or severity of adverse effects. Endovascular cooling with a proactive antishivering regimen can be accomplished in awake stroke patients. Further studies are needed to establish the safety and efficacy of this approach.
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J Stroke Cerebrovasc Dis · Jan 2005
Painless acute aortic dissection with a left hemiparesis: a case report.
We report a patient with completely painless acute aortic dissection who presented with transient left hemiparesis. A 59-year-old male presented to our Emergency Department with left-sided weakness of sudden onset. We therefore suspected cerebrovascular accident. ⋯ The cycle of symptom appearance and recovery recurred 3 times over a period of a few minutes. The final diagnosis was acute aortic dissection (DeBakey type II Stanford type A). Completely painless acute aortic dissection who presented with only neurologic symptoms, which made the diagnosis of acute aortic dissection extremely difficult.
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J Stroke Cerebrovasc Dis · Nov 2004
Effect of contrast material (Levovist) infusion on peak systolic velocity in middle cerebral artery using transcranial color-coded duplex sonography.
It is of crucial importance to predict the presence of stenosis in cerebral artery before occurrence of a stroke. To determine stenosis in the middle cerebral artery (MCA), we examined the effect of contrast agent (Levovist) infusion on transcranial color-coded duplex sonography (TCCD). TCCD was performed in 24 patients with MCA stenosis determined by angiography and/or magnetic resonance angiography, and 42 patients without MCA stenosis were also examined as the control group. ⋯ Difference between precontrast and postcontrast infusion was significantly greater in the stenosis group than in the control group (p < 0.05). We conclude that PSV tends to be underestimate in poor visualization of vessels. To improve accuracy of PSV measurement, contrast enhancement material should be used.
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J Stroke Cerebrovasc Dis · Sep 2004
Determining the appropriateness of selected surgical and medical management options in recurrent stroke prevention: a guideline for primary care physicians from the National Stroke Association work group on recurrent stroke prevention.
Despite a decade of successful clinical trials for stroke prevention, substantial gaps exist in the application and implementation of this information in community practice. The frequency of guideline use is low, and there remains controversy regarding the standard of practice. Patients with stroke may have multiple risk factors and concomitant stroke mechanisms, factors that are not addressed in stroke clinical trials and guideline statements. ⋯ Appropriateness was less where bleeding or surgical risk was excessive. Using consensus evidence from clinical trials, we have developed recurrent stroke prevention guidelines for routine and more complex patient scenarios according to appropriateness methodology. Broad application of these guidelines in primary practice promises to reduce the burden of recurrent stroke.