Paediatric anaesthesia
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Paediatric anaesthesia · Sep 2020
Age-related cerebrovascular carbon dioxide reactivity in children with ventricular septal defect younger than 3 years.
Impaired cerebrovascular reactivity to carbon dioxide was proposed to contribute to neurological morbidity in children undergoing cardiac surgery. The objective of this study was to assess carbon dioxide reactivity and regional cerebral oxygen saturation in children younger than 3 years. ⋯ Abnormal carbon dioxide reactivity is prevalent in children younger than 3 years and the degree varies according to age.
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Paediatric anaesthesia · Sep 2020
Observational StudyEffect of etomidate on systemic and regional cerebral perfusion in neonates and infants with congenital heart disease: A prospective observational study.
Neonates and infants with congenital heart disease undergoing general anesthesia have an increased risk for critical cardiovascular events. Etomidate produces very minimal changes in hemodynamic parameters in older children with congenital heart disease. There is a lack of studies evaluating the effect of etomidate on systemic and regional cerebral perfusion in neonates and infants with congenital heart disease. ⋯ Etomidate 0.4mg kg-1 does not impair systemic or regional cerebral perfusion in neonates or infants with congenital heart disease.