Paediatric anaesthesia
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Paediatric anaesthesia · Apr 2023
Needleless inhaled anesthesia with sevoflurane: advantages of a simplified approach for children with spinal muscular atrophy undergoing intrathecal administration of nusinersen.
Intrathecal nusinersen administration, a fundamental step in the treatment of spinal muscular atrophy, is challenging in children. ⋯ In this single-center experience, needleless general anesthesia with inhaled sevoflurane without imaging guidance has been shown to be feasible for children with spinal muscular atrophy undergoing lumbar puncture for nusinersen administration.
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Paediatric anaesthesia · Apr 2023
Ketamine-Dexmedetomidine combination (KETODEX) for sedation in pediatric major surgery in a low-income country.
Anorectal malformations are one of the most frequent congenital malformations treated by pediatric surgeons. In low-income countries, the surgical and anesthetic management of children in need of these procedures can be challenging. ⋯ We present a series of four cases of anorectal malformations corrections in Guinea Bissau, in children up to 13 months of age, under regional anesthesia and sedation with ketodex, a mixture of ketamine and dexmedetomidine (in a proportion of 1 mg to 1 μg). No child developed respiratory depression requiring airway intervention or supplemental oxygen, or had hemodynamic instability.