Pharmacoepidemiology and drug safety
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Pharmacoepidemiol Drug Saf · Apr 2013
Frequency and nature of drug-drug interactions in the intensive care unit.
Drug-drug interactions (DDIs) may compromise patient safety. However, there are no good estimates of their frequency or understanding of their nature in the intensive care unit (ICU). The objective of this study was to determine the frequency and nature of potential DDIs (pDDIs) in the ICU when assessed in light of documented and perceived clinical relevance. ⋯ There are many potential DDIs with high perceived relevance in the ICU that appear to require attention and follow-up. Computerized decision support may help reduce the number of pDDIs but needs to be tailored to the environment in which it operates.
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Pharmacoepidemiol Drug Saf · Mar 2013
Comparative StudyA survey of adult awareness and use of medicine containing acetaminophen.
To compare awareness, use of acetaminophen, and preferences for receiving information aimed at reducing acetaminophen overdose. ⋯ Acetaminophen use is common, and supratherapeutic exposure may be of concern in users of opioids. Knowledge of which drugs contain acetaminophen appears inadequate; better labeling and proactive education from professionals may be impactful.
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Pharmacoepidemiol Drug Saf · Feb 2013
Retraction Of PublicationRetraction. "Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery" by F. Krummenauer, S. Kurz and H.B. Dick.
The following article from Pharmacoepidemiology and Drug Safety, “Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery” by F. Krummenauer, S. Kurz and H. ⋯ Kurz and H. B. Dick previously published in the European Journal of Medical Research Volume 10, Issue 2, Pages 71–75, 2005.
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Pharmacoepidemiol Drug Saf · Dec 2012
Prevalence and correlates of exceeding the labeled maximum dose of acetaminophen among adults in a U.S.-based internet survey.
Acetaminophen is a commonly used analgesic; excessive doses can lead to liver damage. We sought to determine the proportion of acetaminophen users exceeding the recommended maximum daily dose of 4 g and identify correlates of such behavior. ⋯ The results estimate the proportion of acetaminophen users exceeding 4 g in a group of U.S. adults, identify potentially modifiable attitudes and knowledge associated with such use, and characterize subpopulations at higher risk.