American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Aug 2015
Brain metabolite differences in one-year-old infants born small at term and association with neurodevelopmental outcome.
We assessed brain metabolite levels by magnetic resonance spectroscopy (MRS) in 1-year-old infants born small at term, as compared with infants born appropriate for gestational age (AGA), and their association with neurodevelopment at 2 years of age. ⋯ Infants born small show brain metabolite differences at 1 year of age, which are correlated with later neurodevelopment. These results support further research on MRS to develop imaging biomarkers of abnormal neurodevelopment.
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Am. J. Obstet. Gynecol. · Aug 2015
Mode of delivery of twin gestation with very low birthweight: is vaginal delivery safe?
The purpose of this study was to determine whether planned vaginal delivery is associated with increased risk of perinatal death and morbidity in twin pregnancies that are complicated by a very low birthweight of the second twin. ⋯ Vaginal delivery of very low birthweight twins is associated with an increased risk of intraventricular hemorrhage, regardless of presentation. Because of the small sample size and the retrospective cohort design, large prospective randomized studies are needed.
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Am. J. Obstet. Gynecol. · Aug 2015
Observational StudyLabor patterns in women attempting vaginal birth after cesarean with normal neonatal outcomes.
We sought to describe labor patterns in women with a trial of labor after cesarean (TOLAC) with normal neonatal outcomes. ⋯ Labor duration for TOLAC was slower compared to nulliparous labor, particularly for induced labor. By improved understanding of the rates of progress at different points in labor, this new information on labor curves in women undergoing TOLAC, particularly for induction, should help physicians when managing labor.
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Am. J. Obstet. Gynecol. · Jul 2015
Randomized Controlled TrialVaginal progesterone for the prevention of preterm birth in twin gestations: a randomized placebo-controlled double-blind study.
The purpose of this study was to investigate the use of vaginal progesterone for the prevention of preterm delivery in twin pregnancies. ⋯ In nonselected twin pregnancies, vaginal progesterone administration does not prevent preterm delivery and does not reduce neonatal morbidity and death.
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Am. J. Obstet. Gynecol. · Jul 2015
Is fetal cerebroplacental ratio an independent predictor of intrapartum fetal compromise and neonatal unit admission?
We sought to evaluate the association between fetal cerebroplacental ratio (CPR) and intrapartum fetal compromise and admission to the neonatal unit (NNU) in term pregnancies. ⋯ Lower fetal CPR, regardless of the fetal size, was independently associated with the need for operative delivery for presumed fetal compromise and with NNU admission at term. The extent to which fetal hemodynamic status could be used to predict perinatal morbidity and optimize the mode of delivery merits further investigation.