JNMA; journal of the Nepal Medical Association
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JNMA J Nepal Med Assoc · Apr 2007
Case ReportsAcute liver failure caused by hepatitis E virus and paracetamol.
Acute liver failure is characterized by severe and sudden liver cell dysfunction leading to hepatic encephalopathy and hepatic coagulopathy in a person without history of liver disease in the past. This catastrophic illness can rapidly progress to coma and death from cerebral edema and multi organ dysfunction. ⋯ This report describes a case of acute liver failure in which probably both the agents were involved. The patient recovered with antidote therapy and maximum supportive care.
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JNMA J Nepal Med Assoc · Apr 2007
Comparative StudyLow birth weight at term: relationship with maternal anthropometry.
The objective of this study was to determine the relationship of maternal anthropometry with low birth weight at term. This study was conducted at the Maternity Hospital, Thapathali, from 6th December 2004 to 30th January 2005. It was a prospective, hospital based, comparative study, carried out in 308 women who had delivered singleton live babies at term. ⋯ On multiple logistic regression analysis, only low maternal weight was powerful enough to remain significant (OR 2.84 95% CI 1.34-5.99). From these results, it can be concluded that low maternal anthropometric measurements have a definite role in causing LBW babies at term. Among the studied variables, maternal weight showed the strongest influence on low birth weight.
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To study the clinical profile of Henoch Schönlein Purpura [HSP] in children. A retrospective case series of 30 consecutive children with a diagnosis of HSP, with special focus on clinical manifestations. Two cases with unusual features are described in detail. ⋯ Knee and ankle involvement occurred in more than 3/4th of the patients with arthritis. Vesciculobullous lesions were seen in two patients while one patient had rheumatic fever. Most children with HSP will have classical manifestation of the disease but diagnostic confusion can occur in those with atypical or absent cutaneous features at the onset.