European journal of emergency medicine : official journal of the European Society for Emergency Medicine
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In intensive care units arterial blood sampling is routine for analysing acid-base and oxygenation status. In nonintensive departments arterial blood sampling is seldom performed. Venous blood sampling is routine but not usually analysed for acid-base and oxygenation status. This study describes the correlation between arterial and peripheral, central and mixed venous pH, PCO2 and PO2 in a wide range of adult patients. ⋯ The venous values of pH, corrected for bias, can give arterial values which are within reasonable laboratory and clinical acceptance criteria. For PCO2 this is also true, except for peripheral blood, where the standard deviation is outside laboratory acceptance criteria but within clinical acceptance criteria. For PO2 the arteriovenous differences are not randomly distributed and even for PO2
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The use of ketamine for pediatric sedation in the Emergency Department for painful procedures has become increasingly popular. Ketamine is a safe and effective sedative for diagnostic or therapeutic procedures in the Emergency Department. Sedation with this dissociative agent produces a rapid onset action, potent analgesia, adequate sedation, amnesia and minimal side effects. We report a case of prolonged sedation and airway complications after administration of an inadvertent intramuscular ketamine overdose in a healthy child.
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The management of methanol poisoning includes early antidote therapy to inhibit the metabolism of methanol to formate. Ethanol and fomepizole are both effective, but recently fomepizole has been preferred, although there is no scientific evidence that the use of fomepizole is a superior therapeutic strategy compared with the use of ethanol combined with haemodialysis. The same patient was admitted twice to our emergency department with methanol poisoning. ⋯ In the Belgian healthcare system, we found that fomepizole treatment was three times as expensive as ethanol treatment, and the majority of costs are not reimbursed. Fomepizole antidote therapy, compared with ethanol, has fewer reported side effects, but is more expensive. In hospitals where dialysis is easily available, ethanol antidote therapy should still be considered, especially if similar cost differences exist within the healthcare system one is working in.