Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
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Ann. Allergy Asthma Immunol. · Apr 1995
Multicenter Study Comparative Study Clinical TrialDose-ranging comparative evaluation of cetirizine in patients with seasonal allergic rhinitis.
Cetirizine, an H1-receptor antagonist, has been studied for the relief of seasonal and perennial allergic rhinitis, one of the most common allergic disorders in the United States. Unlike newer antihistamines that can have interactions with other medications, including some macrolide antibiotics and some antifungal agents, cetirizine has not been associated with adverse events consequent to interaction with drugs that depend on hepatic enzymes for their metabolism. ⋯ Dose titration of cetirizine may allow for greater efficacy and quality of life, especially for patients with refractory symptoms of allergic rhinitis in whom therapy with single-dose antihistamines has failed.
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Ann. Allergy Asthma Immunol. · Apr 1995
Case ReportsRecurrent anaphylaxis due to unrecognized latex hypersensitivity in two healthcare professionals.
Anaphylaxis is a potentially fatal immediate-type reaction and intense effort may be required to identify the allergen responsible. In some cases, a "hidden" allergen may be responsible that is not apparent in spite of careful clinical assessment. ⋯ Although latex is widely recognized as a cause of anaphylaxis, it can still be unrecognized in some cases of recurrent anaphylaxis. Latex must be considered as a "hidden" cause of anaphylaxis, particularly in health care workers.