Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
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Ann. Allergy Asthma Immunol. · Sep 1999
Clinical usefulness of patch and challenge tests in the diagnosis of cell-mediated allergy to betalactams.
Literature reports dealing with cell-mediated allergy to betalactams have appeared with increasing frequency in the last years. ⋯ Delayed allergy to betalactams (mainly to aminopenicillins) may be exerted by a cell-mediated response. Patch tests and tolerance challenges are extremely useful and safe for diagnosis and further clinical treatment of these patients, helping to identify safe alternative betalactam molecules that could be successfully tolerated by the allergic subjects.