Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
-
Ann. Allergy Asthma Immunol. · Dec 2015
Randomized Controlled Trial Multicenter Study Clinical TrialTimothy specific IgE levels are associated with efficacy and safety of timothy grass sublingual immunotherapy tablet.
Regional pollen allergen exposure differences may induce variable sensitization profiles that could affect allergen immunotherapy efficacy and safety. ⋯ Sensitization profiles varied by region. Trends toward higher efficacy and increased TRAE incidence in subjects with higher pretreatment Phl p IgE levels were observed.
-
Ann. Allergy Asthma Immunol. · Nov 2015
Clinical TrialRelation between stress and cytokine responses in inner-city mothers.
Women in poor urban neighborhoods have high rates of stress and allergic diseases, but whether stress or stress correlates such as depression promote inflammatory and type 2 cytokine responses is unknown. ⋯ Composite measurements of stressors, perceived stress, or depression were not positively related to proinflammatory or type 2 cytokine responses in these young urban women. These data do not support the hypothesis that these factors promote cytokine responses associated with allergy.
-
Ann. Allergy Asthma Immunol. · Nov 2015
The impact of anxiety and depression on outpatients with asthma.
Anxiety and depression may frequently affect patients with asthma. However, the findings of several studies are partially conflicting and conducted in selected cohorts. ⋯ The present real-life study indicates that anxiety and depression are common and relevant comorbidities in asthmatic outpatients and are associated with uncontrolled asthma and lower ACT scores. Thus, assessment of comorbid mental disorders should be performed in common practice.
-
Ann. Allergy Asthma Immunol. · Nov 2015
Factors associated with the course of egg allergy in children.
The risk factors that affect persistence of egg allergy are under investigation. ⋯ Baseline egg white sIgE levels, baseline gastrointestinal system involvement, concomitant cow's milk allergy, and anaphylaxis with egg may predict a more severe course of egg allergy with late resolution. Moreover, egg white sIgE levels and gastrointestinal symptoms after egg exposure seem to increase the risk of anaphylaxis with egg.