Investigative radiology
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Investigative radiology · Oct 2010
Comparative StudyDynamic contrast-enhanced magnetic resonance imaging evaluation of VX2 carcinoma in a rabbit model: comparison of 1.0-M gadobutrol and 0.5-M gadopentetate dimeglumine.
To compare the enhancement characteristics and diagnostic performance of 1.0-M gadobutrol with those of 0.5-M gadopentetate dimeglumine in rabbit VX2 tumor models. ⋯ Using a 3.0-T magnet, equivalent doses of 1.0-M gadobutrol-enhanced MR imaging showed a superior degree of enhancement for a VX2 tumor than 0.5-M gadopentetate dimeglumine-enhanced MR imaging, and a significant preference for readers was noted for 1.0-M gadobutrol-enhanced MR imaging.