Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
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Clin. Microbiol. Infect. · Mar 2020
ReviewTransition from intravenous to oral antimicrobial therapy in patients with uncomplicated and complicated bloodstream infections.
The role of oral antimicrobial agents in the management of bloodstream infections (BSI) is currently evolving. ⋯ Recent studies demonstrate that early transition from intravenous to oral therapy is a feasible and effective strategy in most patients with BSI due to Gram-negative bacteria, obligate anaerobic bacteria and Candida species. Oral antimicrobial combinations may be considered in select patients with complicated Gram-positive BSI after 10-14 days of intravenous therapy. Future studies will determine the role of oral agents for switch therapy in uncomplicated Gram-positive BSI.
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Clin. Microbiol. Infect. · Mar 2020
Community-acquired pneumonia in the emergency department: an algorithm to facilitate diagnosis and guide chest CT scan indication.
The aim was to create and validate a community-acquired pneumonia (CAP) diagnostic algorithm to facilitate diagnosis and guide chest computed tomography (CT) scan indication in patients with CAP suspicion in Emergency Departments (ED). ⋯ Our CAP diagnostic algorithm may help reduce CAP misdiagnosis and optimize the use of chest CT scan.