Respirology : official journal of the Asian Pacific Society of Respirology
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparative study of pleurodesis using talc slurry and bleomycin in the management of malignant pleural effusions.
Differing success rates of various pleurodesis agents have been reported in the management of malignant pleural effusions. A randomized clinical trial was conducted to compare the efficacy of two commonly used agents, talc and bleomycin, for the pleurodesis of malignant pleural effusions. ⋯ These results indicate that talc slurry is as effective as bleomycin in preventing early recurrence of malignant pleural effusions. Pleurodesis with talc instead of bleomycin can result in significant cost savings.