International journal of clinical practice
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Int. J. Clin. Pract. · Dec 2021
Association of antihypertensives during hospitalization with acute respiratory failure in patients with viral pneumonia: A population-based case-control study.
We aimed to identify associations between the risk of acute respiratory failure (ARF) and types of antihypertensive agents in patients with viral pneumonia. ⋯ Patients with viral pneumonia who received α-blockers, β-blockers, thiazides or angiotensin receptor blockers during hospitalisation had a lower risk of developing ARF.
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Int. J. Clin. Pract. · Dec 2021
Expression of Leptin mRNA as Non-Invasive Biomarker in Type 2 Diabetes Mellitus.
Leptin, an adipocyte-derived signalling molecule that plays important role in the regulation of energy balance, body weight and glucose metabolism. ⋯ This study shows that the reduced leptin mRNA expression level is significantly associated with T2DM and could be used as a predictive and diagnostic biomarker for T2DM.
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Int. J. Clin. Pract. · Dec 2021
Treatment of maternal depression in low-income women: A feasibility study from Kilifi, Kenya.
To test the feasibility and acceptability of a group psychosocial intervention called Learning Through Play (LTP) plus Culturally adapted Cognitive Behaviour Therapy (CaCBT) for depressed Kenyan mothers with children aged 0-36 months. ⋯ This study represents the first feasibility research on integrated parenting intervention in Kenya. The results indicated that culturally adapted LTP plus CaCBT is feasible and acceptable in a low-income setting of Kenya. There is now a need to study the clinical and cost-effectiveness of LTP plus CaCBT in an appropriately powered larger randomised control trial, with a longer follow-up period.