European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
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Eur. J. Paediatr. Neurol. · Mar 2016
Clinical experience of intravenous lacosamide in infants and young children.
To review our clinical experience with intravenous (iv) lacosamide (LCM) in children less than 12 years old. ⋯ This is the first published retrospective study of very young critically ill children receiving iv LCM. The acute tolerability at this dosing range represents a positive trend and need confirmation from larger studies.
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Eur. J. Paediatr. Neurol. · Mar 2016
Ketamine-based procedural sedation and analgesia for botulinum toxin A injections in children with cerebral palsy.
Adequate procedural sedation and analgesia (PSA) is essential to reduce pain and distress for children undergoing intramuscular botulinum toxin (BoNT-A) injections. This study describes our institution's experience with ketamine-based PSA in terms of safety and efficacy in children with cerebral palsy receiving BoNT-A injections. ⋯ Administration of ketamine-based PSA for intramuscular BoNT-A procedures in children can be both safe and efficacious.