Fertility and sterility
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Fertility and sterility · Nov 1995
Randomized Controlled Trial Clinical TrialFollicular fluid levels of midazolam, fentanyl, and alfentanil during transvaginal oocyte retrieval.
To investigate the time course of changes in follicular fluid (FF) concentrations of midazolam (Roche Products Ltd., Welwyn Garden City, United Kingdom), fentanyl (Janssen Pharmaceuticals Ltd., Wantage, United Kingdom), and alfentanil (Janssen Pharmaceuticals Ltd.) during ultrasound-guided transvaginal oocyte collection. ⋯ We conclude that midazolam, fentanyl, and alfentanil are found in FF after a single IV dose, but further investigation needs to be undertaken to investigate any potential influence on fertilization and implantation rates.