American journal of veterinary research
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Comparative Study
Calculation of variables describing plasma nonvolatile weak acids for use in the strong ion approach to acid-base balance in cattle.
To calculate values for the total concentration of nonvolatile weak acids (Atot) and the effective dissociation constant for nonvolatile weak acids (Ka) of bovine plasma and to determine the best method for quantifying the unmeasured strong anion concentration in bovine plasma. ⋯ Calculated values for Atot, Ka, and the SIG equation should facilitate application of the strong ion approach to acid-base disturbances in cattle.