American journal of veterinary research
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To characterize the pharmacokinetics of remifentanil in conscious cats and cats anesthetized with isoflurane. ⋯ The disposition of remifentanil in cats was characterized by a high clearance. Isoflurane anesthesia significantly decreased the volume of the central compartment, likely by decreasing blood flow to vessel-rich organs.
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Comparative Study
Evaluation of induction characteristics and hypnotic potency of isoflurane and sevoflurane in healthy dogs.
To determine induction characteristics and the minimum alveolar concentration (MAC) at which consciousness returned (MACawake) in dogs anesthetized with isoflurane or sevoflurane. ⋯ Sevoflurane resulted in a more rapid induction than did isoflurane. The MACawake for dogs was higher than values reported for both agents in humans. Care should be taken to ensure that dogs are at an appropriate anesthetic depth to prevent consciousness, particularly when single-agent inhalant anesthesia is used.