The Journal of pediatrics
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The Journal of pediatrics · Jun 2017
Brain Perfusion and Diffusion Abnormalities in Children Treated for Posterior Fossa Brain Tumors.
To compare cerebral perfusion and diffusion in survivors of childhood posterior fossa brain tumor with neurologically normal controls and correlate differences with cognitive dysfunction. ⋯ The treatment for MB, but not PA, was associated with globally reduced CBF. Treatment in both tumor types was associated with diffusion abnormalities of the mesial temporal lobe structures. Despite significant perfusion abnormalities in patients with MB, diffusion, but not perfusion, correlated with cognitive outcomes.