The Journal of pediatrics
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The Journal of pediatrics · Nov 2016
Randomized Controlled TrialEffect of Delayed Cord Clamping on Systemic Blood Flow: A Randomized Controlled Trial.
To determine whether delayed cord clamping improves systemic blood flow compared with immediate cord clamping in very preterm infants in the first 24 hours. ⋯ Delayed cord clamping had no effect on systemic blood flow measured as mean lowest SVC flow in the first 24 hours in infants <30 weeks' gestation.
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The Journal of pediatrics · Oct 2016
Case ReportsExtending the Clinical Phenotype of Adenosine Deaminase 2 Deficiency.
Adenosine deaminase 2 deficiency is an autoinflammatory disease, characterized by various forms of vasculitis. We describe 5 patients with adenosine deaminase 2 deficiency with various hematologic manifestations, including pure red cell aplasia, with no evidence for vasculitis.
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The Journal of pediatrics · Oct 2016
Observational StudyCortisol Correlates with Severity of Illness and Poorly Reflects Adrenal Function in Pediatric Acute Respiratory Distress Syndrome.
To test the association between random cortisol and severity of illness in a "real-world" application of current guidelines. ⋯ In children with ARDS with vasopressor-dependent shock, low cortisol correlated with lower severity of illness. Random cortisol was a poor method of diagnosing adrenal insufficiency, and a strategy of hydrocortisone replacement for cortisol < 18 μg/dL did not target a population likely to benefit from hydrocortisone. Future guidelines should reconsider using random cortisol levels alone for assessing adrenal function.
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The Journal of pediatrics · Oct 2016
Observational StudySafety of the Manchester Triage System to Detect Critically Ill Children at the Emergency Department.
To assess the safety of the Manchester Triage System in pediatric emergency care for children who require admission to the intensive care unit (ICU). ⋯ The Manchester Triage System misclassifies a substantial number of children who require ICU admission. Modifications targeted at young children and children with a comorbid condition could possibly improve safety of the Manchester Triage System in pediatric emergency care.