J Reprod Med
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Case Reports
Can digoxin and sotalol therapy for fetal supraventricular tachycardia and hydrops be successful? A case report.
Neonatal survival and prognosis are closely linked with development of hydrops in cases of sustained fetal tachycardia. Several antiarrhythmic medications are available for conversion to sinus rhythm. ⋯ Digoxin and sotalol therapy can be successful in blocking likely nodal reentry in sustained fetal supraventricular tachycardia, thus allowing resolution of hydrops with a favorable outcome.
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Randomized Controlled Trial Multicenter Study
French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study.
A previous open study demonstrated that French maritime pine bark extract (Pycnogenol) may soothe menstrual pain in dysmenorrhea. We thus investigated the effects of Pycnogenol on menstrual pain in a double-blind study. ⋯ The analgesic-sparing effect of Pycnogenol increases with duration of supplementation and benefits persist even after discontinuation.
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Comparative Study
Efficacy of rectal misoprostol as second-line therapy for the treatment of primary postpartum hemorrhage.
To assess the efficacy of rectal misoprostol as second-line therapy in the management of primary postpartum hemorrhage (PPH) as compared to methylergonovine maleate. ⋯ This limited study suggests that rectal misoprostol is comparable to methergine as second-line therapy for the treatment of 1 primary postpartum hemorrhage.
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Although fetal hydrothorax is uncommon, perinatal mortality from it is high. The clinical course of fetal hydrothorax is highly variable. Despite some cases of spontaneous resolution, fetal hydrothorax progresses to nonimmune hydrops because of impaired venous return and congestive cardiac failure due to compression in many cases. Although the effect of thoracoamniotic shunting is established, the procedure is invasive and involves some risks. ⋯ Thoracentesis is a comparatively simple procedure for mothers and fetuses and should be the first choice for treating fetal hydrothorax.
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To investigate the association of functional E and P selectin polymorphisms with severe preeclampsia. ⋯ The polymorphisms tested are not associated with the risk of severe preeclampsia.