The American journal of clinical nutrition
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Clinical Trial Controlled Clinical Trial
Dietary fat content alters insulin-mediated glucose metabolism in healthy men.
A high dietary fat intake is involved in the pathogenesis of insulin resistance. ⋯ A high-fat, low-carbohydrate intake reduces the ability of insulin to suppress endogenous glucose production and alters the relation between oxidative and nonoxidative glucose disposal in a way that favors storage of glucose.