The American journal of clinical nutrition
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Randomized Controlled Trial Comparative Study Clinical Trial
Effect of a phase advance and phase delay of the 24-h cycle on energy metabolism, appetite, and related hormones.
The disruption of the circadian system has been associated with the development of obesity. ⋯ The main effect of circadian misalignment, either phase advanced or phase delayed, is a concomitant disturbance of the glucose-insulin metabolism and substrate oxidation, whereas the energy balance or sleep is not largely affected. Chronically eating and sleeping at unusual circadian times may create a health risk through a metabolic disturbance. This trial was registered at the International Clinical Trials Registry Platform (http://apps.who.int/trialsearch/) as NTR2926.
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Randomized Controlled Trial Comparative Study
Diet and exercise weight-loss trial in lactating overweight and obese women.
Current evidence suggests a combined treatment of postpartum weight loss of diet and exercise. However, to our knowledge, neither their separate and interactive effects nor long-term outcomes have been evaluated. ⋯ Dietary treatment provided clinically relevant weight loss in lactating postpartum women, which was sustained at 9 mo after treatment. The combined treatment did not yield significant weight or body-composition changes beyond those of dietary treatment alone.