Arch Gen Psychiat
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Randomized Controlled Trial Clinical Trial
Maintenance imipramine therapy for secondary depression in schizophrenia. A controlled trial.
Although recent studies have documented the benefit of adjunctive antidepressant medication for the short-term treatment of certain patients with operationally defined syndromes of postpsychotic depression, the value of maintenance adjunctive antidepressant treatment in this circumstance has not been properly established. ⋯ These results support the clinical value of maintenance adjunctive imipramine therapy among initially responsive patients with postpsychotic depressions.