Pediatr Crit Care Me
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Pediatr Crit Care Me · May 2005
Effect of one-rescuer compression/ventilation ratios on cardiopulmonary resuscitation in infant, pediatric, and adult manikins.
Optimal chest compression to ventilation ratio (C:V) for one-rescuer cardiopulmonary resuscitation (CPR) is not known, with current American Heart Association recommendations 3:1 for newborns, 5:1 for children, and 15:2 for adults. C:V ratios influence effectiveness of CPR, but memorizing different ratios is educationally cumbersome. We hypothesized that a 10:2 ratio might provide adequate universal application for all age arrest victims. ⋯ C:V ratio and manikin size have a significant influence on the number of effective compressions and ventilations delivered during ideal, metronome-paced, one-rescuer CPR. Low ratios of 3:1, 5:1, and 10:2 favor ventilation, and high ratios of 15:2 favor compression, especially in adult manikins. Rescuers subjectively preferred C:V ratios of 10:2 and 15:2 over 3:1 or 5:1. Infant CPR caused less exertion and subjective fatigue than pediatric or adult CPR technique, without significant difference by C:V ratio. We speculate that a universal 10:2 C:V ratio for one-rescuer layperson CPR is physiologically reasonable but warrants further study with particular attention to educational value and technique retention.
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Pediatr Crit Care Me · May 2005
ReviewIdentification of central venous catheter-related infections in infants and children.
To define central venous catheter-related infections in infants and children for the purpose of enrolling children in sepsis studies, for epidemiology and surveillance studies, and for clinical management. ⋯ For the purposes of enrolling patients with sepsis in clinical trials, only patients who meet criteria for definite catheter-related bloodstream infection should be categorized as having the catheter as the infection source. Because many patients suspected of having catheter-related bloodstream infection do not have positive blood culture results, which makes the confirmation of infection difficult, we recommend that these patients not be enrolled in sepsis trials. Because catheter tips are often not obtained for culture in children, the epidemiology of catheter-associated bloodstream infection (bloodstream infection in a patient who has a central venous catheter and no other obvious source of infection) is better understood than the epidemiology of confirmed catheter-related bloodstream infection in infants and children. Definitions for catheter-related bloodstream infection that compare the through-catheter and peripheral culture for time to positivity or for quantitative growth are unlikely to be falsely positive, but sensitivity requires further validation.
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In 2004, a consensus meeting of critical care and infectious disease experts was organized to review and make recommendations on current definitions of infections, sepsis, and organ failure for neonates and children and for the predisposing conditions leading to these diseases. Among the infections leading to sepsis, meningococcemia is so distinguishable that a separate article on its diagnosis and management was thought to be warranted. ⋯ Early recognition and treatment of likely meningococcal sepsis has led to decreased mortality. Since the start of vaccination against serogroup C, the prevalence of this disease has decreased. Not only the possible presence of a meningococcal sepsis is important, but also the assessment of the shock state and the severity of disease and the possible presence of meningoencephalitis. There are also a number of genetic predispositions determining the severity of disease. The only three randomized trials in this disease have led to the conclusion that mortality is not a stable end point. Improvement in organ function, morbidity (including amputations), and functional outcome are better outcome measures.