Pediatr Crit Care Me
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Pediatr Crit Care Me · Jul 2004
Randomized Controlled Trial Clinical TrialNoninvasive positive-pressure ventilation in children with lower airway obstruction.
Mechanical ventilation of patients with severe lower airway obstruction presents significant risks; therefore, avoiding the intubation in these patients has been a principal goal of clinical management. Noninvasive positive-pressure ventilation has been shown to be effective in treating adults with chronic obstructive pulmonary disease, but its use has not been studied prospectively in children with acute obstructive lower airways disease. The objective of this study was to determine whether noninvasive mask ventilation improved respiratory function in children with asthma and other obstructive lower airways diseases. ⋯ We conclude that noninvasive ventilation can be an effective treatment for children with acute lower airway obstruction.
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Pediatr Crit Care Me · Jul 2004
Randomized Controlled Trial Clinical TrialInspiratory work of breathing is not decreased by flow-triggered sensing during spontaneous breathing in children receiving mechanical ventilation: a preliminary report.
To determine the effect of pressure-trigger (PT) and flow-trigger (FT) sensing on the work of breathing (WOB) during spontaneous, unsupported breathing in children receiving mechanical ventilation. ⋯ FT may not decrease WOB compared with PT for unsupported spontaneous breathing in children receiving mechanical ventilation. However, when lung compliance is decreased, FT sensing may be advantageous in decreasing the WOB.
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Pediatr Crit Care Me · Jul 2004
Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children.
To study the association of timing, duration, and intensity of hyperglycemia with pediatric intensive care unit (PICU) mortality in critically ill children. ⋯ Hyperglycemia is common in critically ill children. Peak BG and duration of hyperglycemia are independently associated with mortality in our PICU. A prospective, randomized trial of strict glycemic control in this subset of critically ill children who are at high risk of mortality is both warranted and feasible.