British medical bulletin
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British medical bulletin · Mar 2016
The aetiopathogenesis of fatigue: unpredictable, complex and persistent.
Chronic fatigue syndrome is a common condition characterized by severe fatigue with post-exertional malaise, impaired cognitive ability, poor sleep quality, muscle pain, multi-joint pain, tender lymph nodes, sore throat or headache. Its defining symptom, fatigue is common to several diseases. ⋯ By adopting this approach, the field can examine issues regarding aetiopathogenesis and treatment, with relevance for future research and clinical practice.
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British medical bulletin · Mar 2016
ReviewFreezing and non-freezing cold weather injuries: a systematic review.
The debilitating impact of cold weather on the human body is one of the world's oldest recorded injuries. The severe and life-changing damage which can be caused is now more commonly seen recreationally in extreme outdoor sports rather than in occupational settings such as the military. The diagnosis and treatment of these injuries need to be completed carefully but quickly to reduce the risk of loss of limb and possibly life. Therefore, we have conducted a systematic review of the literature surrounding cold weather injuries (CWIs) to ascertain the epidemiology and current management strategies. ⋯ The treatment of non-freezing CWIs with their long-term follow-up.
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Uterus transplantation (UTx) is introduced as the first treatment for absolute uterine factor infertility (AUFI), affecting 1:500 fertile aged women. This review presents potential patients, research and human UTx cases. ⋯ All new activities in human UTx within the coming years should be conducted as prospective observational studies, and data should also be collected within an international registry.