Dermatitis
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Review Meta Analysis
Association between the IL10 -1082A>G (rs1800896) single-nucleotide polymorphism and atopic dermatitis: a systematic review and meta-analysis.
The potentially functionally relevant IL10 -1082A>G (rs1800896) promoter region single-nucleotide polymorphism has been implicated in the pathogenesis of atopic dermatitis (AD). Although this relationship has been studied extensively, these association studies were limited by small sample size. ⋯ This study was unable to find a direct association between IL10 -1082A>G and AD. Further studies are needed to reveal the contributions of haplotype and gene-gene and gene-environment interaction effects involving this single-nucleotide polymorphism to AD.