Arch Iran Med
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Genetic analysis of non-syndromic hearing loss (NSHL) has been challenged due to marked clinical and genetic heterogeneity. Today, advanced next-generation sequencing (NGS) technologies, such as exome sequencing (ES), have drastically increased the efficacy of gene identification in heterogeneous Mendelian disorders. ⋯ To the best of our knowledge, this nonsense variant (NM_001079812.3):c.3610C>T (p. Arg1204Ter) is the first report of the DIAPH1 gene variant for autosomal dominant non-syndromic hearing loss (ADNSHL) in Iran.
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Detecting the correlation of conflict rate within provinces over time provides a better understanding for health policymakers in identifying potential causes. The purpose of this study was to assess the trend of conflict rate in 31 provinces of Iran using the growth mixture model (GMM). ⋯ Our study showed the increasing growth of conflict in the last years in most provinces of Iran. Necessary interventions are important to prevent the rising conflict rate due to the various effects of conflict on psychological, social, and health factors.
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Review Historical Article
Health Conditions in Tehran's Girl Schools from 1927 to 1934: A Brief Survey.
A new model of relations emerged in schools after the establishment of new educational centers in Iran in the mid-Qajar era. The cultural authorities of the time were particularly interested in school health, which was adopted as a principle from the European, particularly French, school systems. ⋯ The findings reveal that since the mid-first Pahlavi era, officials from the Ministry of Science became increasingly involved in the issue of health, which resulted in institutionalization of health and medical examination of students, establishment of the School Health Office, publication of theoretical health discussions in magazines, and teaching of health principles to students, thereby improving the level of health in Tehran schools during the study period. The study aims to provide Iranian physicians and health policymakers with a review of this historical experience.
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Little is known about the predictors of left ventricular ejection fraction (LVEF) -an important predictor of mortality- after primary percutaneous coronary intervention (PCI) in low- and middle-income countries. ⋯ Adherence to clopidogrel, short door-balloon time, high creatinine clearance, and lower baseline LVEF were associated with preserved/improved LVEF, while history of MI, high CK-MB, and multi-vessel disease were predictors of reduced LVEF. Long-term drug adherence should be considered for LVEF improvement in low- and middle-income countries.