Chinese Med J Peking
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Chinese Med J Peking · Mar 1999
Association of polymorphism of apolipoprotein E gene with coronary heart disease in Han Chinese.
To investigate the association between apolipoprotein E (apoE) gene polymorphism and coronary heart disease(CHD) in Han Chinese. ⋯ Hot start PCR assay is considered a rapid and simple technique for apoE genotyping. This method is suitable for routine laboratories and large scale population studies. Genetic polymorphism of the apoE gene might contribute to the determination of serum lipid profile and the development of CHD among Han Chinese.
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Chinese Med J Peking · Mar 1999
Structure and function of alleles in the 3' end region of human apoB gene.
To study the structure of alleles in the 3' end of the apoB gene in Han, Mongolian and Tibetan populations in China as well as the roles in the regulation of gene expression. ⋯ More alleles with different number of tandem repeats in 3' end of apoB gene exist in the Chinese populations. The alleles in 3' end minisatellite of human apoB gene could control the expression of the gene itself.