Niger J Clin Pract
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Comparative Study
Relation of iron stores to oxidative stress in type 2 diabetes.
Recent studies revealed elevated serum ferritin levels predict new-onset type 2 diabetes. Further studies proved ferritin to be an important and independent predictor of the development of diabetes. The link between hyperglycemia, enhanced free radical activity (oxidative stress) and serum iron and its stores (serum ferritin levels) levels is not clear. ⋯ Serum ferritin level in the present study is found to be higher in the newly diagnosed cases and lower in those patients suffering from diabetes for more than 10 years. This study probably suggests that serum ferritin can represent either as a pro-oxidant or as an antioxidant in a time-dependent manner.
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Although substance abuse is fairly common among adolescents, poisoning from Datura stramonium (a broadleaf annual erect herb with spine-covered seed capsule) is uncommon in children and has not been reported in our locality. We present the case of two children admitted at the Children Emergency Room of a teaching hospital following ingestion of extract of Datura stramonium. ⋯ Early presentation and the presence of an eyewitness contributed to the very good outcome in these index cases. In this report, we discussed the symptomatology and management of Datura toxicity in children.
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Case Reports
Exertional abdominal pain as a symptom of secondary pulmonary hypertension in mitral stenosis.
We report a rare presentation of mitral stenosis (MS). MS is a common valvular disease, the first manifestation of which is usually easy fatigability and exertional dyspnea. ⋯ This is the first report of a case of mitral stenosis presenting with exertional abdominal pain as the first manifestation. This case report describes the clinical characteristics of a 55-year-old woman with mitral stenosis and severe pulmonary hypertension, whose first symptom was exertional abdominal pain.