Obstetrics and gynecology
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Obstetrics and gynecology · Jun 2015
ReviewEbola virus disease and Marburg disease in pregnancy: a review and management considerations for filovirus infection.
The largest-ever recorded outbreak of viral hemorrhagic fever is ongoing. As a result of the epidemic and rural nature of outbreaks, little is published about the Filovirus infections Ebola virus disease and Marburg disease in pregnancy. This review of viral hemorrhagic fever focusing on Marburg and Ebola uses knowledge of disease in nonpregnant individuals and pregnancy-specific data to inform management for pregnant women. ⋯ Regardless of maternal survival, fetal loss rates are nearly 100% in Filovirus infection, likely resulting from unchecked transplacental and hematogenous viral spread. High fetal loss rates support the placenta as a difficult-to-eradicate Filovirus infection reservoir. In conclusion, the management of Filovirus infection in pregnancy should focus on stabilizing the mother with intensive monitoring and aggressive fluid and electrolyte repletion as well as maintaining strict infection control to minimize transmission to others.
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Obstetrics and gynecology · Jun 2015
Enoxaparin dosing after cesarean delivery in morbidly obese women.
To compare the adequacy of venous thromboembolism prophylaxis based on anti-Xa concentrations between weight-based enoxaparin dosing and body mass index (BMI)-stratified dosing in morbidly obese women after cesarean delivery. ⋯ II.
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Obstetrics and gynecology · Jun 2015
Pregnancy outcomes after antepartum tetanus, diphtheria, and acellular pertussis vaccination.
To evaluate pregnancy outcomes of women who received tetanus, diphtheria, and acellular pertussis (Tdap) vaccination at or after 32 weeks of gestation. Outcomes from consecutive pregnancies during which the mother received Tdap were also analyzed. ⋯ II.
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Obstetrics and gynecology · Jun 2015
Racial and ethnic disparities in maternal morbidity and obstetric care.
To evaluate whether racial and ethnic disparities exist in obstetric care and adverse outcomes. ⋯ II.