Pediatric clinics of North America
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Pediatr. Clin. North Am. · Feb 2015
Review Historical ArticleEvolution of modern treatment of childhood acute leukemia and cancer: adventures and battles in the 1970s and 1980s.
This article summarizes the adventures and explorations in the 1970s and 1980s in the treatment of children with leukemia and cancer that paved the way for the current success in childhood cancers. Indeed, these were adventures and bold steps into unchartered waters. Because childhood leukemia the most common of the childhood cancers, success in childhood leukemia was pivotal in the push toward cure of all childhood cancers. The success in childhood leukemia illustrates how treatment programs were designed using clinical- and biology-based risk factors seen in the patients.
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Pediatr. Clin. North Am. · Feb 2015
ReviewSupportive care in pediatric oncology: oncologic emergencies and management of fever and neutropenia.
Advancements in the care of children with cancer have, in part, been achieved through improvements in supportive care. Situations that require prompt care can occur at the time of presentation as well as during treatment. This article discusses the approach to children with fever and neutropenia, a complication encountered daily by care providers, as well as oncologic emergencies that can be seen at the time of a child's initial diagnosis: hyperleukocytosis, tumor lysis syndrome, superior vena cava syndrome, and spinal cord compression.