Anesteziologiia i reanimatologiia
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Anesteziol Reanimatol · Mar 2014
Randomized Controlled Trial Comparative Study[Comparison of dexmedetomidine and propofol for short-term sedation in early postoperative period after cardiac surgery].
To compare the efficacy of Dexmedetomidine and Propofol for short-term controlled sedation and analgesia in the early postoperative period after cardiac surgery. ⋯ To compare with Propofol Dexmetomedine induces less sedation level and more often provides retrograde amnesia with the same duration of mechanical ventilation and awakening rate. Dexmetomedine provides its own analgesic effect and shortens the length of patient's stay in ICU. Bradycardia was noted more frequently in Dexmedetomidine while arterial hypotension, general malaise and delirium--in Propofol group.
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Anesteziol Reanimatol · Mar 2014
Comparative Study Controlled Clinical Trial[Prophylaxis of blood loss and allogenic blood transfusion with fibrinolysis inhibitors produced in Russian Federation in patients undergoing cardiac surgery].
Significant bleeding during cardiac surgery, enough to cause re-exploration and/or blood transfusion, increases morbidity and mortality. Bleeding after cardiopulmonary bypass is related to multiple factors: endothelial dysfunction, thrombocytopenia, dilution coagulopathy. ⋯ Data from rotational thromboelastometry measurements (Rotem Gamma Pentapharm, Germany), blood loss and transfusion were collected. The results confirm that used in the study antifibrinolytics: the lysine analogues aminomethylbenzoic acid and epsilon aminocaproic acid prevent hyperfibrinolysis after cardiopulmonary bypass as well as aprotinin.
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Anesteziol Reanimatol · Mar 2014
[Intensive care and anaesthesia for blood loss in obstetrics. Clinical guidelines were approved by the Presidium of the Federation of Anaesthesiologists and Reanimatologists of Russia on 15/09/13 in Krasnoyarsk. Sectional commission in "Anesthesiology and Reanimatology" of the Ministry of Health of the Russian Federation approved the guidelines for submission to the Ministry of Health of the Russian Federation on 11/15/13].
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Anesteziol Reanimatol · Mar 2014
Randomized Controlled Trial Comparative Study[Role of migraine history in the development of postoperative nausea and vomiting in patients undergoing general and combined general-epidural anesthesia].
To assess the role of migraine history in the development of postoperative nausea and vomiting (PONV) in patients undergoing general and combined general-epidural anaesthesia. ⋯ Migraine history is a significant risk factor of PONV. Epidural component of anaesthesia does not effect on frequency of PONV in women with migraine, but Droperidolum use allows increasing the frequency of PONV.
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Anesteziol Reanimatol · Mar 2014
[Assessment of pain relief in patients receiving different variants of multimodal analgesia after major gynecological surgery].
The major gynecology surgery generally results in severe postoperative pain. Currently multimodal analgesia concept is widely used for the aim of postoperative pain relief optimization. ⋯ One way to solve the problem is appearing in daily practice nefopam--centrally acting non-opioid analgesic that inhibits reuptake of serotonin, norepinephrine, and dopamine and also mitigates glutamatergic neurotransmission. In this trial we tried to assess the postoperative daily used analgesia quality and potency of preemptive multimodal analgesia model consisted of nefopam, ketoprofen, paracetamol and morphine.