Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC
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J Obstet Gynaecol Can · Sep 2007
Randomized Controlled Trial Comparative StudyRectal misoprostol versus oxytocin in the management of the third stage of labour.
To compare the effect of rectal misoprostol with intramuscular oxytocin in the routine management of the third stage in a rural developing country. ⋯ Rectal misoprostol 800 microg is as effective as 10 IU intramuscular oxytocin in minimizing blood loss in the third stage of labour. Rectal misoprostol has a lower incidence of side effects than the equivalent oral dose. This confirms the utility of misoprostol as a safe and effective uterotonic for use in the rural and remote areas of developing nations where other pharmacologic agents may be less feasible.