World journal of gastroenterology : WJG
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World J. Gastroenterol. · Jun 2013
Epidemiology, clinical-treatment patterns and outcome in 256 hepatocellular carcinoma cases.
To analyze the epidemiology, clinical characteristics, treatment patterns and outcome in hepatocellular carcinoma (HCC) patients. ⋯ This study showed that, between 2000-2005 and 2005-2010, the number of HCV-related HCC decreased, non-viral/non alcoholic etiologies increased and of surveillance programs were more frequently applied.
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World J. Gastroenterol. · May 2013
Protective effects of two Lactobacillus plantarum strains in hyperlipidemic mice.
To investigate the effects of Lactobacillus plantarum (L. plantarum) CAI6 and L. plantarum SC4 on hyperlipidemic mice. ⋯ L. plantarum CAI6 and L. plantarum SC4 may protect against cardiovascular disease by lipid metabolism regulation and Nrf2-induced antioxidative defense in hyperlipidemic mice.
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World J. Gastroenterol. · May 2013
Neoadjuvant-intensified treatment for rectal cancer: time to change?
To investigate whether neoadjuvant-intensified radiochemotherapy improved overall and disease-free survival in patients with locally advanced rectal cancer. ⋯ The results of this study suggest oxaliplatin chemotherapy has a beneficial effect on overall survival, likely due to an increase in local tumor control.
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World J. Gastroenterol. · May 2013
Sustained virological response: a milestone in the treatment of chronic hepatitis C.
To evaluate the long-term eradication of hepatitis C virus (HCV) infection and liver-related complications in chronically infected patients that have achieved sustained virological response. ⋯ Patients with CHC and SVR show an excellent prognosis with no risk of recurrence and a very low rate of mortality. Our data indicate that virus-eradication following interferon treatment can last up to 20 years.
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World J. Gastroenterol. · Apr 2013
Review Meta AnalysisExtended antimicrobial prophylaxis after gastric cancer surgery: a systematic review and meta-analysis.
To investigate the efficacy of extended antimicrobial prophylaxis (EAP) after gastrectomy by systematic review of literature and meta-analysis. ⋯ We recommend that EAP should not be used routinely after gastrectomy until more high-quality RCTs are available.