Vestnik khirurgii imeni I. I. Grekova
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Vestn. Khir. Im. I. I. Grek. · Jan 2007
Comparative Study[Experience with using of solutions of hydroxyethyl starch (refortan and voluven) in neuroanesthesiology].
The investigation has shown that solutions of hydroxyethyl starch included in complex infusion therapy facilitate stabilization of hemodynamics in neurosurgical patients during surgery. Refortan exerts a more pronounced effect on the indices of hemodynamics as compared with voluven, but its modifying action on the hemostasis system is also more pronounced. These medicines used in doses 6-8 ml/kg fail to have substantial effects on efficiency of hemostasis in the brain wound and do not increase risk of postoperative hemorrhagic complications.