Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Oct 2022
Unravelling the relationship between serum 25-hydroxyvitamin D levels and trabecular bone score in U.S. adults.
Trabecular bone score (TBS) is a novel way for clinicians to evaluate bone quality. It is directly associated with the mechanical strength of bones and helps predict fractures. Vitamin D, a secosteroid that enhances calcium absorption, is commonly used to strengthen the skeletal system. ⋯ Our study shows that low serum levels of 25(OH)D may decrease the TBS, which represents the skeletal microarchitecture and is a fracture risk factor in individuals with normal T‑scores.
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Pol. Arch. Med. Wewn. · Oct 2022
The serum concentration of brain-derived neurotrophic factor is lower in ambulatory and clinically stable patients with more advanced systolic heart failure.
Brain‑derived neurotrophic factor (BDNF) is decreased in heart failure (HF), but whether serum BDNF concentration is related to the severity of HF with reduced left ventricular (LV) ejection fraction (LVEF) below 50% is uncertain. ⋯ HF patients with LVEF below 50% and lower serum BDNF concentration present more advanced cardiac remodeling and dysfunction than individuals with higher BDNF. Potential mechanisms and clinical consequences of these findings require further investigation.
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Pol. Arch. Med. Wewn. · Oct 2022
Changes in osteoporosis therapy in postmenopausal women from the RAC-OST-POL Study: a 10-year follow-up.
Therapeutic regimens for osteoporosis are the key elements in the management of osteoporotic patients. ⋯ Changes in the therapy of postmenopausal women with osteoporosis, observed in a 10‑year follow‑up of the RAC‑OST‑POL study, indicated that the level of care did not improve in this group of patients.
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Pol. Arch. Med. Wewn. · Oct 2022
Dynamic change of sST2 predicts major adverse cardiovascular events in patients with ST-segment elevation myocardial infarction.
Introduction：The predictive value of soluble suppression of tumorigenicity 2 (sST2) for the occurrence of major adverse cardiovascular events (MACEs) in patients with ST‑segment elevation myocardial infarction (STEMI) remains unclear. ⋯ The increase in plasma sST2 levels from admission to 24 hours post pPCI has a potential value for independently predicting the incidence of coronary revascularization and cardiac rehospitalization at 1 year in patients with STEMI.