British medical journal
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British medical journal · Jan 1970
Malignant hyperpyrexia during anaesthesia: possible association with subclinical myopathy.
The members of a family in whom three malignant hyperpyrexial deaths occurred during anaesthesia were studied by means of serum creatine phosphokinase estimations. Abnormally high levels were found in many asymptomatic relatives. ⋯ Possibly sudden unexplained deaths under varying circumstances are a further expression of this underlying abnormality. A possible clue to the anticipation of future cases of malignant hyperpyrexia has been found, and it is suggested that relatives of previous cases be investigated.
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British medical journal · Jan 1970
Randomized Controlled Trial Clinical TrialReduction of incidence of prematurity by folic acid supplementation in pregnancy.
Folic acid administered to pregnant Bantu, whose diet is low in folate, was associated with a significant reduction in the incidence of prematurity. No such effect could be demonstrated in White patients subsisting on an average Western diet. This suggests that folate deficiency may contribute to the "pregnancy wastage" in populations whose dietary folate intake is low, and is a further indication for folic acid supplementation during pregnancy in these groups.