British medical journal
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Br Med J
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British medical journal · Sep 1968
Clinical TrialClinical trial of 6 per cent hydroxyethyl starch (a new plasma expander).
No adverse effects were seen in 29 patients given an intravenous infusion of 6% hydroxyethyl starch solution. Platelet counts had fallen by eight hours after infusion, but had reached pretransfusion levels by 24 hours. Two patients developed unusual bleeding post-operatively, which was possibly due to the infusion. Further investigations on the first stage of coagulation and prothrombin generation in patients receiving hydroxyethyl starch are required.